Toward stratified treatments for bipolar disorders.

Eur Neuropsychopharmacol. 2015 Mar;25(3):283-94. doi: 10.1016/j.euroneuro.2014.12.006. Epub 2015 Jan 2. Hasler G1, Wolf A2. Abstract In bipolar disorders, there are unclear diagnostic boundaries with unipolar depression and schizophrenia, inconsistency of treatment guidelines, relatively long trial-and-error phases of treatment optimization, and increasing use of complex combination therapies lacking empirical evidence. These suggest that the current definition(…)